Comments on planning and the 3 Tesla MRI.

نویسنده

  • William F Haning
چکیده

n Februars I . 2004. facult members ol’the John A. Burns School of \ledicinc md stati of Quccn s \Icdn, ii C cntc I Drs. Linda Chang. Thomas Ernst. Christine Cloak. Andrew Stender. Cecilia Shikuma, and Napapon Sailasuta held a neuro imaging conference at Queen’s Medical Center. The meeting was to initiate plans for a new, functional magnetic resonance imaging (fMRI) research facility. Almost exactly a year later. February 25, 2005, the 3Tesla MRI was dedicated and open for service. It’s all very strange. this planning business, At some point in hu man history. somehod deviated from the usual stimulus-response mode of. “I’m hungry, it’s time to kill a ook mammoth. and started sketching out a plan. Probably humble designs. like deciding whether to hunt for an antelope tomorrow, or maybe a 200—pound prehistoric rabbit. But some impulse toward variety——some bridging of a neural arch took place thatpmje ted a possibi I itv and aiiruiputed an outcome. What leap of faith was that. that inipelled a series of evolutions? Planning is one of those peculiarly human activities that keep endless numbers of committees all a-twitter, harassed secretar ies and aides consuming antidepressants. and the Franklin Covey people rich. It may be the antithesis of happiness. I have never seen a Golden Retriever jotting in her Palm Pilot, nor even any of the subtler signs, such as restlessness or inattention while in the middle of playing ith other dogs, or abrupt awakening soaked in doggie sweat. Sadl . this is stuff that Inioui,is do all the time when they ha e incomplete planning in their heads. When my dog becomes agitated. it is generally in response to some item on no schedule. such as openinL’ a can of dog tood. Even if planning isn’t the antithesis of happiness, it certainly doesn’t seem clearly correlated. People do not speak ‘ ith joyful anticipation of their involvement in a new planning committee. and it is rare that we gleefully set a dinner (late with our insurance agents. Or. take Planned Parenthood-—ou can talk about planning a child all ou ant, but the kid is or she isn’t. Try to convince a newborn that she is the successful outcome of a lengthy planning process and that you are overjoyed at her arrival. Her view is that she is hungry and von have just interrupted the longest nap of her life. lntrivuingl. that same bridging of a neural arch that took place le\k million ears ago ma\ be i-esponsiblc for the patholog that h:is dnen this research initiatis e. Consider that the ability to plan and the ahilit to recall constitute two features of human intelligence that are most profound I affected in addiction or in the sub—cortical dementia that can accompany ad ancing HIV disease .N1 patients ith addictions have false anticipations upon which they predicate their use ot drugs. and certainly have put aside any pretenses of planning, delaying gratification, or setting about an orderl process of character development. Some of Dr. Cecilia Shikuma’s patients and subjects will seek a pattern of conduct that is flO longer acces sible, a memory that eludes them .And at the root of both behaviors may he a similar process. A possibility that Dr. Chang proposes is inflammation of the brain tissues. The strangeness of this business of planning is emphasized when how much that is planned is not realized. If there was ever a better demonstration of the persistence of human will in spite ofadversitv or common sense. I do not know it. Reinforcement is. in almost all cases, not merely intermittent. hut rare. Paul Ehrlich’s magic bullet Salarsan 606. arsphenamine. was compound #1914 in the series of planned candidates. In a terrible perversion of planning. my alcoholic patients daily plan great events: they then engage in a simple uncontrolled clinical trial with n = I. slug back 250 ml. of’ grain alcohol or equivalent, and experience the same old outcome: inebriation and disappointment. Yet, they gamely persist. expect different outcomes, or seek reminiscently an outcome that was briefly realized. years or decades ago: a romantic moment, an idyll. an ecstasy. We are almost equally astonished hen things planned come to pass. but s e don’t recognize them. In 914. a series of friendl alliances, the industrial development of Europe. and the enormous armament of e er\ small country of the time required intensive and highly sophisticated planning. Combined. they had a reasonably predictable outcome as World War I. ‘ et every bod was astonished hen it happened. We thought that it s as peace and prospentY that we s crc planning. not war. Most of human planned endca\ or doesn’t come about, yet astonishingl\ we carry on, like Sisvphus. Why? Occasionally it generates some wonderful results, that have great and happy, if subtle or distant consequences. The “planned” 3 Tesla MRI is now a reality. Dr. Linda Chang, Dr. Thomas Ernst, and colleagues get to plan some possibilities such as:

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عنوان ژورنال:
  • Hawaii medical journal

دوره 64 4  شماره 

صفحات  -

تاریخ انتشار 2005